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Opiate drugs
by Dori Stehlin

Opiate drugs are another class of pain-relieving prescription drugs.
Commonly prescribed opiates include morphine, codeine, hydromorphone
(Dilaudid), and meperidine (Demerol). (In some states, some forms of codeine are sold without a prescription in limited amounts.) Most of these drugs are derived from opium, the juice of the poppy flower.

Opiate drugs work by altering the transmission of pain messages in the brain and spinal cord, blocking pain messages or altering their character. The pain-blocking action of the opiates can be enhanced by taking aspirin, ibuprofen or acetaminophen at the same time as the opiate. This hits pain with a "double-whammy." The NSAIDS block the pain at the site of injury, while the opiates suppress in the brain any remaining pain.

Unfortunately, the effect of opiates on the brain isn't limited to pain control. Opiates can cause drowsiness, nausea, constipation, and unpleasant mood changes in some people. However, sometimes simply trying a different opiate may be all that's needed to reduce these side effects.

(Dori Stehlin is a staff writer for FDA Consumer)

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